Discover health via phenotypes
A phenotype is a set of traits, like blood pressure or body shape, that reflect how your genes and environment interact. In health, recognizing your phenotype helps identify disease risk and guide the best treatments.
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Sticky Situation: Aortic Stenosis
Might we be on the verge of medical therapy to prevent a mechanical problem?
Cheating Death: The Heart Attack Survivor
Why we continue to fail at secondary prevention, despite being presented with the obvious
There’s an App for That! Why Risk Calculators Fail to Detect Heart Attacks
Risk Calculators and why they Fail to detect heart attacks
Too Much of a GOOD Thing? Dysfunctional HDL
Why high HDL-C is not always protective. A common cause of residual risk, particularly in women
A Picture is Worth a Thousand Words: Coronary Artery Calcium Scores
CAC - it’s not a risk factor, it is the disease
Statins: Apocalypse or Pleiotropic Nirvana? Why Statins Will Not End Civilization, Nor Cure All Ills
Statins are not the root of all evil but they don’t belong in the drinking water either
“Little Napoleon Complex”: Lp (a)
An LDL-like atherogenic lipoprotein that is largely hereditary and increases risk
The Straw That Breaks the Camel’s Back
Lean Mass Hyper‑Responder (LMHR) — A Cardiometabolic Phenotype
The Enigma of HFpEF
Heart Failure with Preserved Ejection Fraction (HFpEF)
Why It Hides in Plain Sight — and Why We Finally Have Weapons to Fight It
Atherogenic Triad: The Deadly Phenotype of High Triglycerides, Low HDL-C and High sdLDL-P
The Deadly Phenotype of High Triglycerides, Low HDL-C and High sdLDL-P
Don’t Forget Your Beans - Kidney Disease
Obstructive Sleep Apnea: The Cardiometabolic Bad Actor
Hiding in Plain Sight: Familial Hypercholesterolemia (FH)
A common genetic condition. A lifetime of risk. Still routinely missed.
Precious Cargo — Pregnancy as a Cardiovascular Stress Test
Why gestational hypertension and dysglycemia matter long after delivery